A capacidade do corpo humano de se curar é verdadeiramente notável. De cortes a queimaduras, muitas vezes testemunhamos a incrível habilidade da pele de se regenerar e cicatrizar. No entanto, há momentos em que esse processo parece se estagnar, deixando-nos intrigados e preocupados. Por que algumas lesões simplesmente não cicatrizam? Vamos explorar alguns dos motivos por trás desse fenômeno intrigante.

1. Biofilme

Uma das principais razões pelas quais algumas lesões não cicatrizam é a presença de biofilme, que é um grupo de micro-organismos (fungos, bactérias e protozoários) que ficam aderidos na superfície da ferida1. O biofilme geralmente ocorre em cinco etapas, as quais contempla sua adesão, liberação de sinais químicos, formação de microcolônias, multiplicação de micro-organismos e nova colonização1. Eles podem invadir uma ferida, interferindo no processo de cicatrização e até piorando a condição.

Fonte: Chronic Wound Biofilms: Pathogenesis and Potential Therapies

2. Má Circulação Sanguínea

A circulação sanguínea desempenha um papel crucial na cicatrização de feridas, fornecendo oxigênio e nutrientes essenciais às células da pele. Quando a circulação sanguínea é comprometida, seja devido a condições médicas subjacentes como diabetes ou aterosclerose, ou a hábitos prejudiciais como fumar, o processo de cicatrização pode ser significativamente prejudicado2. Feridas em áreas do corpo com má circulação, como os pés em pacientes diabéticos, podem levar mais tempo para cicatrizar.

Imagem de um desenho de uma perna, com ula lesão no maléolo medial e acima um recorte da imagem mostrando a parte interna das veias com uma alteração importante de um vaso venoso, que se encontra dilatado e tortuoso.
Fonte: Blog Giovanna Guarinello- 5 problemas de circulação e seus sintomas.

3. Doenças Subjacentes

Certas condições médicas, como diabetes, doenças autoimunes, distúrbios vasculares, deficiências de vitaminas, alteração da coagulação, desnutrição, uso de corticosteroides, radioterapia podem interferir na capacidade do corpo de cicatrizar feridas 3. Por exemplo, a neuropatia diabética pode causar danos nos nervos, resultando em perda de sensibilidade nas extremidades e aumentando o risco de lesões não detectadas que podem se tornar úlceras de difícil cicatrização.

4. A Idade

À medida que envelhecemos, a capacidade do corpo de se curar naturalmente pode diminuir. A pele fica mais fina e menos elástica, e o sistema imunológico pode não ser tão eficaz na resposta a lesões e infecções. Isso pode resultar em cicatrização mais lenta e maior risco de complicações em feridas3.

Conclusão

Embora o corpo humano seja extraordinariamente hábil na cicatrização de feridas, há uma variedade de fatores que podem interferir nesse processo. Desde infecções persistentes até condições médicas subjacentes e entender por que algumas lesões não cicatrizam pode ajudar a orientar o tratamento e prevenir complicações futuras. Se você estiver enfrentando dificuldades com uma ferida que não cicatriza, é importante buscar orientação do estomaterapeuta para identificar e tratar quaisquer problemas subjacentes.

Referências:

1- SOBENFEE. Recomendação Brasileira para o gerenciamento de biofilme em feridas crônicas e complexas. 2018; 31: 28-58.

2- Junior AEA, Carbinatto FM, Coelho VHM, Bagnato VS. Feridas: Um desafio para a saúde pública. São Carlos: Editora, 2019; 216.

3- Campos ACL, Branco AB, Groth AK. Cicatrização de feridas. ABCD, arq. bras. cir. dig. 2007; 20(1): 51-58.

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Enfermeira pela USP, com especialização em saúde do adulto e do idoso pela USP e estomaterapeuta com habilitação em laserterapia. Atuo no tratamento avançado de lesões, estomias e na reabilitação de pessoas com incontinência fecal e urinária

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